[et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/06\/AdobeStock_279577524-compressed-scaled.jpg” custom_padding=”40px||40px||true|false” custom_padding_tablet=”30px||30px||true|false” custom_padding_phone=”30px||30px||false|false” locked=”off” global_colors_info=”{}” custom_css_after_last_edited=”off|desktop”][et_pb_row _builder_version=”4.18.0″ _module_preset=”default” custom_margin=”|auto|40px|auto|false|false” custom_margin_tablet=”||30px||false|false” custom_margin_phone=”||30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” text_orientation=”center” custom_margin=”||14px||false|false” custom_padding=”||0px|||” header_text_align_tablet=”” header_text_align_phone=”left” header_text_align_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n
[\/et_pb_text][et_pb_divider color=”#ffae00″ divider_weight=”2px” _builder_version=”4.21.0″ _module_preset=”default” width=”300px” width_tablet=”250px” width_phone=”150px” width_last_edited=”on|phone” module_alignment=”center” custom_margin=”||0px||false|false” custom_padding=”||2px||false|false” module_alignment_tablet=”center” module_alignment_phone=”left” module_alignment_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text module_class=”projectCategorie” _builder_version=”4.18.0″ _dynamic_attributes=”content” _module_preset=”default” text_font_size=”14px” link_text_color=”#444444″ text_orientation=”center” text_orientation_tablet=”center” text_orientation_phone=”left” text_orientation_last_edited=”on|phone” global_colors_info=”{}” link_text_color__hover_enabled=”on|hover” link_text_color__hover=”#115894″]@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9jYXRlZ29yaWVzIiwic2V0dGluZ3MiOnsiYmVmb3JlIjoiIiwiYWZ0ZXIiOiIiLCJsaW5rX3RvX3Rlcm1fcGFnZSI6Im9uIiwic2VwYXJhdG9yIjoiICIsImNhdGVnb3J5X3R5cGUiOiJwcm9qZWN0X2NhdGVnb3J5In19@[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” module_class=”rowDetails” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”off|phone”][et_pb_blurb title=”Date : ” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.20.2″ _module_preset=”default” header_text_color=”#444444″ custom_padding=”||4px|||” animation=”off” header_font_size_last_edited=”off|desktop” global_colors_info=”{}”]2023
\n[\/et_pb_blurb][et_pb_blurb title=”State of progress:” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n
In progress<\/p>\n
[\/et_pb_blurb][et_pb_blurb title=”Objectives: ” use_icon=”on” font_icon=”||fa||900″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n
Better understand the effects of microgravity on the human body
Test artificial gravity and exercise as countermeasures<\/p>\n
[\/et_pb_blurb][et_pb_blurb title=”Partners:” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n
ESA, CNES, MEDES<\/p>\n
[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.19.3″ _module_preset=”default” use_background_color_gradient=”on” background_color_gradient_stops=”#ededed 0%|#ffffff 100%” min_height=”697.5px” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.19.3″ _module_preset=”default” min_height=”574.5px” custom_padding=”||0px|||” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.19.3″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” custom_padding=”||0px|||” global_colors_info=”{}”]<\/p>\n
MEDES is currently carrying out a microgravity simulation study using the bed rest model at its Space Clinic. Commissioned by the French (CNES) and European (ESA) space agencies , the study, named BRACE (Bed Rest with Artificial gravity and Cycling Exercise), includes 12 healthy male volunteers. The study lasted 88 days (including 60 days in bed).<\/p>\n
<\/p>\n
The main objective of this study is to investigate whether artificial gravity combined with a cycling exercise helps to prevent and \/ or reduce the physiological effects induced by 60 days of anti-orthostatic bedrest.<\/strong><\/p>\n \u00a0<\/strong><\/p>\n 2 countermeasures are being tested:<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.19.3″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2023\/05\/MEDES_Centrifgeuse_MD.jpg” title_text=”MEDES_Centrifgeuse_MD” _builder_version=”4.21.0″ _module_preset=”default” width=”100%” module_alignment=”right” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.19.5″ _module_preset=”default” background_color=”gcid-7752e2bb-64ea-447a-88d9-5280a721cd77″ global_colors_info=”{%22gcid-7752e2bb-64ea-447a-88d9-5280a721cd77%22:%91%22background_color%22%93}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.19.3″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.19.3″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” custom_padding=”||0px|||” global_colors_info=”{}”]<\/p>\n 14 european scientific teams will assess the changes in the cardiovascular, metabolic, musculoskeletal, neuro-sensorial, haematological, and immunological systems. They have been selected by the ESA evaluation committees.<\/p>\n The various tests will provide a better understanding of the effects of prolonged bed rest on the various physiological systems, their interrelationships, and the effects of the two countermeasures. In addition to the measurements proposed by the scientists, a battery of standard measurements exploring the various physiological systems is also being carried out. These measures have been used for over ten years in all bedrest studies carried out in Europe. They enable us to evaluate the different countermeasures tested in the same way, and to compare their effectiveness with each other.<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.19.3″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2023\/05\/MEDES_prodigima-BRACE-032_MD.jpg” title_text=”MEDES_prodigima-BRACE-032_MD” _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.19.5″ _module_preset=”default” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.19.5″ _module_preset=”default” custom_margin=”|125px||140px||” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.19.5″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2023\/05\/MEDES_prodigima-BRACE-052_MD.jpg” title_text=”MEDES_prodigima-BRACE-052_MD” _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.19.5″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” custom_padding=”||0px|||” global_colors_info=”{}”]<\/p>\n The main selection and inclusion criteria were as follows:<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n The selection will be carried out in several phases:<\/p>\n <\/strong>At the end of the selection process, 12 candidates were selected.<\/p>\n 12 volunteers were be allocated to one of the three compared groups:<\/p>\n <\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.21.0″ _module_preset=”default” background_color=”gcid-7752e2bb-64ea-447a-88d9-5280a721cd77″ global_colors_info=”{%22gcid-7752e2bb-64ea-447a-88d9-5280a721cd77%22:%91%22background_color%22%93}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.19.3″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” custom_padding=”||0px|||” global_colors_info=”{}”]<\/p>\n Each volunteer is hospitalized for 88 days, including 60 days in bed.<\/p>\n The hospitalization period comprises:<\/p>\n Furthermore, subjects will have to come back to MEDES 30, 360 and 720 days after the period of hospitalization for three follow-up visits.<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.19.3″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2023\/05\/MEDES_prodigima-BRACE-143_MD.jpg” title_text=”MEDES_prodigima-BRACE-143_MD” _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_row _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n The study began on April 4 and will end in early July with 12 volunteers. An equivalent 2nd phase will be carried out in early 2024, also with 12 volunteers. Recruitment will take place in autumn 2023.<\/p>\n Applications will open in autumn 2023.<\/p>\n [\/et_pb_text][et_pb_button button_url=”\/etude-dalitement-brace-2eme-phase\/” button_text=”More about BRACE recruitment (in french)” button_alignment=”left” button_alignment_tablet=”left” button_alignment_phone=”left” button_alignment_last_edited=”on|phone” admin_label=”Voir toutes les actualit\u00e9s” module_class=”bouton_recrutement_volontaire” _builder_version=”4.21.0″ _module_preset=”default” custom_button=”on” button_text_size=”13px” button_text_color=”#FFFFFF” button_bg_use_color_gradient=”on” button_bg_color_gradient_direction=”0deg” button_bg_color_gradient_stops=”#0e86a7 0%|#131434 100%” button_border_width=”1px” button_border_color=”#FFFFFF” button_border_radius=”5px” button_letter_spacing=”1px” button_font=”Oswald|||on|||||” button_use_icon=”off” custom_margin=”15px||||false|false” custom_padding=”10px|20px|10px|20px|true|true” custom_padding_tablet=”8px|20px|8px|20px|true|true” 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header_2_text_color=”#000000″ header_2_font_size=”22px” custom_margin=”||10px||false|false” custom_margin_tablet=”||0px||false|false” custom_margin_phone=”||0px||false|false” custom_margin_last_edited=”on|tablet” animation_direction=”bottom” header_font_size_tablet=”40px” header_font_size_phone=”30px” header_2_text_align_tablet=”center” header_2_text_align_phone=”center” header_2_text_align_last_edited=”on|tablet” header_2_font_size_tablet=”18px” header_2_font_size_phone=”20px” animation_duration_tablet=”0ms” animation_duration_phone=”0ms” animation_duration_last_edited=”on|tablet” animation_intensity_slide_tablet=”” animation_intensity_slide_phone=”0%” animation_intensity_slide_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.17.4″ _module_preset=”default” width=”61%” min_height=”72.7px” custom_padding=”||1px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” text_font=”Open Sans||||||||” text_text_color=”#000000″ global_colors_info=”{}”]<\/p>\n News<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”||divi||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.21.0″ _module_preset=”default” background_color=”#D6D6D6″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”\/en\/our-projects\/” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n Our projects<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”u||divi||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.21.0″ _module_preset=”default” background_color=”#5e5e5e” custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”\/en\/contact\/” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n A question ?<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”||fa||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” disabled_on=”off|off|off” module_class=”boutonFixe” _builder_version=”4.21.0″ _module_preset=”default” background_color=”gcid-54b54a1e-9ad0-4545-b0eb-2cf1c6cd3982″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”\/en\/space-clinic\/become-a-volunteer\/” hover_enabled=”0″ global_colors_info=”{%22gcid-54b54a1e-9ad0-4545-b0eb-2cf1c6cd3982%22:%91%22background_color%22%93}” sticky_enabled=”0″]<\/p>\n Become a volunteer ?<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”||fa||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.21.0″ _module_preset=”default” background_color=”gcid-4eb119fd-82df-4fd0-ae59-ab7f1c508199″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”\/en\/space-clinic\/clinical-studies\/” hover_enabled=”0″ global_colors_info=”{%22gcid-4eb119fd-82df-4fd0-ae59-ab7f1c508199%22:%91%22background_color%22%93}” sticky_enabled=”0″]<\/p>\n Our clinical studies<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”s||divi||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”28px” disabled_on=”off|off|off” module_class=”boutonFixe” _builder_version=”4.21.0″ _module_preset=”default” background_color=”#002130″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”\/etude-dalitement-brace-2eme-phase\/” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n New volunteer recruitment for BRACE study<\/p>\n [\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Study evaluating the effects of centrifugation and exercise to prevent the effets of weightlessness.<\/p>\n","protected":false},"author":3,"featured_media":13652,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[80,86,79,76,108,91,75],"project_tag":[],"class_list":["post-15338","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-bed-rest-study","project_category-clinical-research","project_category-clinical-study","project_category-countermeasures","project_category-featurad-project","project_category-physiology-in-microgravity","project_category-space-clinic"],"acf":[],"yoast_head":"\n\n
Medical and scientific tests and examinations<\/h2>\n
Study volunteers<\/h2>\n
\n
\n
\n
The study process<\/strong><\/h2>\n
\n
More information:<\/h3>\n
\n
\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_class=”sectionFixe” _builder_version=”4.18.0″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” positioning=”none” position_origin_f=”center_right” horizontal_offset=”0px” custom_padding=”0px||0px||true|false” custom_css_main_element=”position: fixed !important;||right: 0 !important;||left: unset !important;||top: 57%!important;||transform: translateY(-50%);” locked=”off” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” _builder_version=”4.18.0″ _module_preset=”default” width=”100%” max_width=”100%” custom_padding=”0px||0px||true|false” custom_css_main_element=” overflow: visible !important;” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb image=”https:\/\/www.medes.fr\/wp-content\/uploads\/2023\/04\/Sans-titre-18.png” icon_placement=”left” image_icon_width=”50px” disabled_on=”off|off|off” module_class=”boutonFixe” _builder_version=”4.21.0″ _module_preset=”default” background_color=”#ffae00″ image_icon_custom_margin=”||||false|false” image_icon_custom_padding=”|14px|||false|false” custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”\/en\/ressources\/news\/” global_colors_info=”{}”]<\/p>\n