{"id":13281,"date":"2010-12-01T10:56:42","date_gmt":"2010-12-01T09:56:42","guid":{"rendered":"https:\/\/www.medes.fr\/project\/bed-rest-study-centrifuge-2010\/"},"modified":"2023-06-05T11:51:25","modified_gmt":"2023-06-05T09:51:25","slug":"bed-rest-study-centrifuge-2010","status":"publish","type":"project","link":"https:\/\/www.medes.fr\/en\/project\/bed-rest-study-centrifuge-2010\/","title":{"rendered":"Bed rest study “Centrifuge” (2010)"},"content":{"rendered":"

[et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/06\/AdobeStock_279577524-compressed-scaled.jpg” custom_padding=”40px||40px||true|false” custom_padding_tablet=”30px||30px||true|false” custom_padding_phone=”30px||30px||false|false” locked=”off” global_colors_info=”{}” custom_css_after_last_edited=”off|desktop”][et_pb_row _builder_version=”4.18.0″ _module_preset=”default” custom_margin=”|auto|40px|auto|false|false” custom_margin_tablet=”||30px||false|false” custom_margin_phone=”||30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.18.0″ _dynamic_attributes=”content” _module_preset=”default” text_orientation=”center” custom_margin=”||14px||false|false” custom_padding=”||0px|||” header_text_align_tablet=”” header_text_align_phone=”left” header_text_align_last_edited=”on|phone” global_colors_info=”{}”]@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IjxoMT4iLCJhZnRlciI6IjwvaDE+In19@[\/et_pb_text][et_pb_divider color=”#ffae00″ divider_weight=”5px” _builder_version=”4.18.0″ _module_preset=”default” width=”300px” width_tablet=”250px” width_phone=”150px” width_last_edited=”on|phone” module_alignment=”center” custom_margin=”||0px||false|false” custom_padding=”||2px||false|false” module_alignment_tablet=”center” module_alignment_phone=”left” module_alignment_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text module_class=”projectCategorie” _builder_version=”4.18.0″ _dynamic_attributes=”content” _module_preset=”default” text_font_size=”14px” link_text_color=”#444444″ text_orientation=”center” text_orientation_tablet=”center” text_orientation_phone=”left” text_orientation_last_edited=”on|phone” global_colors_info=”{}” link_text_color__hover_enabled=”on|hover” link_text_color__hover=”#115894″]@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9jYXRlZ29yaWVzIiwic2V0dGluZ3MiOnsiYmVmb3JlIjoiIiwiYWZ0ZXIiOiIiLCJsaW5rX3RvX3Rlcm1fcGFnZSI6Im9uIiwic2VwYXJhdG9yIjoiICIsImNhdGVnb3J5X3R5cGUiOiJwcm9qZWN0X2NhdGVnb3J5In19@[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” module_class=”rowDetails” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”off|phone”][et_pb_blurb title=”Date : ” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.19.5″ _module_preset=”default” header_text_color=”#444444″ animation=”off” global_colors_info=”{}”]<\/p>\n

2010<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”State of progress :” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Ended<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objectives : ” use_icon=”on” font_icon=”||fa||900″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Study of the effects of spaceflight on the human body
Evaluation of artificial gravity as a countermeasure<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Partners :” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

ESA, CNES, MEDES<\/p>\n

[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”60px||60px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” make_equal=”on” _builder_version=”4.19.1″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”on|tablet” custom_css_main_element_tablet=”margin-bottom: 30px !important” custom_css_main_element_phone=”margin-bottom: 30px !important”][et_pb_text admin_label=”Au dernier trimestre 2021″ _builder_version=”4.19.1″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” locked=”off” global_colors_info=”{}”]<\/p>\n

In 2009-2010, MEDES carried out a bed rest study aimed at evaluating artificial gravity, created by a short arm centrifuge, to prevent the effects of weightlessness, simulated by anti-orthostatic bed rest.<\/strong><\/p>\n

The evaluation involved two centrifugation protocols used as a counter-measure to prevent the deterioration brought about in healthy men by 5 days\u2019 anti-orthostatic bed rest.<\/p>\n

It was an ESA-CNES study.<\/strong><\/p>\n

This study was made possible by the installation of a short-arm centrifuge on the Space Clinic’s premises in 2007.<\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.19.1″ _module_preset=”default” use_background_color_gradient=”on” background_color_gradient_stops=”#e8e8e8 0%|#ffffff 100%” background_enable_image=”off” custom_padding=”60px||60px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” make_equal=”on” _builder_version=”4.19.1″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.19.1″ _module_preset=”default” background_enable_image=”off” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”margin-bottom: 30px !important”][et_pb_text admin_label=”Pourquoi une immersion s\u00e8che ?” _builder_version=”4.21.0″ header_2_text_align=”right” background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” header_2_text_align_tablet=”left” header_2_text_align_phone=”left” header_2_text_align_last_edited=”on|tablet” text_orientation_tablet=”left” text_orientation_phone=”left” text_orientation_last_edited=”on|tablet” locked=”off” global_colors_info=”{}”]<\/p>\n

Context<\/h2>\n

One of the aims of the current space programmes is to prepare for future manned interplanetary missions, which may last for up to 3 years (as, for example, to Mars). Exposure to the space environment and particularly weightlessness for such periods leads to physiological changes that involve the cardio-vascular, muscle, bone and neuro-sensory systems.<\/p>\n

Preventive means, also known as \u201ccounter-measures\u201d, are used to combat these deleterious effects of exposure to the space environment and to prepare the astronauts for their return to Earth. The current counter-measures are mostly based on physical exercise (treadmill, bicycle-ergometer) or Lower Body Negative Pressure (or LBNP, a box in which negative pressure is applied to the lower body). They had been tested in previous bed rest studies carried out at the Space Clinic.<\/p>\n

Today, these counter-measures are used by the permanent crews of the International Space Station (ISS) who stay on board for up to 180 days. However, they are only partially effective, probably because they only involve one physiological system at a time (muscles and possibly bones for the exercise, cardio-vascular system for LBNP, etc.).<\/p>\n

Artificial gravity therefore offers a more global approach to the counter-measures issue as it simply simulates the Earth\u2019s gravitational environment and therefore has repercussions for all our physiological systems.<\/strong><\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.19.1″ _module_preset=”default” background_enable_image=”off” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”margin-bottom: 30px !important”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/12\/P36724_MD-1.jpg” title_text=”Volontaire installe dans la centrifugeuse” _builder_version=”4.19.1″ _module_preset=”default” custom_padding=”92px||||false|false” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.19.1″ _module_preset=”default” custom_padding=”102px||102px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ use_custom_gutter=”on” make_equal=”on” custom_padding_last_edited=”off|tablet” _builder_version=”4.19.1″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”on|tablet” custom_css_main_element_tablet=”margin-bottom: 30px !important;” custom_css_main_element_phone=”margin-bottom: 30px !important;”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/12\/DSC_3380.jpg” title_text=”DSC_3380″ _builder_version=”4.19.1″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.19.1″ _module_preset=”default” background_enable_image=”off” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/12\/DSC_3399.jpg” title_text=”DSC_3399″ align=”center” _builder_version=”4.19.1″ _module_preset=”default” max_width=”44%” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.19.1″ _module_preset=”default” background_enable_image=”off” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/12\/DSC_3418.jpg” title_text=”DSC_3418″ _builder_version=”4.19.1″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.19.1″ _module_preset=”default” use_background_color_gradient=”on” background_color_gradient_stops=”#00142b 0%|#1a5d90 100%” custom_padding=”60px||60px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” make_equal=”on” _builder_version=”4.19.1″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.19.1″ _module_preset=”default” background_enable_image=”off” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”margin-bottom: 30px !important”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/12\/DSC_3347-1.jpg” title_text=”DSC_3347″ _builder_version=”4.19.1″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”Au dernier trimestre 2021″ _builder_version=”4.21.0″ text_text_color=”#FFFFFF” header_2_text_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” locked=”off” global_colors_info=”{}”]<\/p>\n

How to study was organised ?<\/h2>\n

12 male volunteers, divided into 3 groups, took part in the study, which took place in the Space Clinic (MEDES) over three 2-week hospitalisation periods at 4 to 5-week intervals.<\/p>\n

Each 2-week hospitalisation period included:<\/p>\n