[et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/06\/AdobeStock_279577524-compressed-scaled.jpg” custom_padding=”40px||40px||true|false” custom_padding_tablet=”30px||30px||true|false” custom_padding_phone=”30px||30px||false|false” locked=”off” global_colors_info=”{}” custom_css_after_last_edited=”off|desktop”][et_pb_row _builder_version=”4.18.0″ _module_preset=”default” custom_margin=”|auto|40px|auto|false|false” custom_margin_tablet=”||30px||false|false” custom_margin_phone=”||30px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.18.0″ _dynamic_attributes=”content” _module_preset=”default” text_orientation=”center” custom_margin=”||14px||false|false” custom_padding=”||0px|||” header_text_align_tablet=”” header_text_align_phone=”left” header_text_align_last_edited=”on|phone” global_colors_info=”{}”]@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IjxoMT4iLCJhZnRlciI6IjwvaDE+In19@[\/et_pb_text][et_pb_divider color=”#ffae00″ divider_weight=”5px” _builder_version=”4.18.0″ _module_preset=”default” width=”300px” width_tablet=”250px” width_phone=”150px” width_last_edited=”on|phone” module_alignment=”center” custom_margin=”||0px||false|false” custom_padding=”||2px||false|false” module_alignment_tablet=”center” module_alignment_phone=”left” module_alignment_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text module_class=”projectCategorie” _builder_version=”4.18.0″ _dynamic_attributes=”content” _module_preset=”default” text_font_size=”14px” link_text_color=”#444444″ text_orientation=”center” text_orientation_tablet=”center” text_orientation_phone=”left” text_orientation_last_edited=”on|phone” global_colors_info=”{}” link_text_color__hover_enabled=”on|hover” link_text_color__hover=”#115894″]@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9jYXRlZ29yaWVzIiwic2V0dGluZ3MiOnsiYmVmb3JlIjoiIiwiYWZ0ZXIiOiIiLCJsaW5rX3RvX3Rlcm1fcGFnZSI6Im9uIiwic2VwYXJhdG9yIjoiICIsImNhdGVnb3J5X3R5cGUiOiJwcm9qZWN0X2NhdGVnb3J5In19@[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” module_class=”rowDetails” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”off|phone”][et_pb_blurb title=”Date : ” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.19.5″ _module_preset=”default” header_text_color=”#444444″ animation=”off” global_colors_info=”{}”]<\/p>\n
2011<\/p>\n
[\/et_pb_blurb][et_pb_blurb title=”State of progress :” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n
Ended<\/p>\n
[\/et_pb_blurb][et_pb_blurb title=”Objective : ” use_icon=”on” font_icon=”||fa||900″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.19.1″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n
Study on the effectiveness of drugs during sleep deprivation<\/p>\n
[\/et_pb_blurb][et_pb_blurb title=”Partner :” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”60px||60px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” global_colors_info=”{}”][et_pb_row _builder_version=”4.18.0″ _module_preset=”default” custom_margin=”||10px||false|false” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”MEDES a men\u00e9 pour l’ESA” _builder_version=”4.19.1″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” locked=”off” global_colors_info=”{}”]<\/p>\n
This study was part of the European <\/strong>PharmaCog<\/strong><\/span> project, which marked the beginning of an ambitious public-private partnership to advance pharmaceutical research for the treatment of Alzheimer’s disease.<\/strong><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”2_3,1_3″ use_custom_gutter=”on” make_equal=”on” _builder_version=”4.19.1″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”2_3″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”on|tablet” custom_css_main_element_tablet=”margin-bottom: 30px !important” custom_css_main_element_phone=”margin-bottom: 30px !important”][et_pb_text admin_label=”Au dernier trimestre 2021″ _builder_version=”4.19.3″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” locked=”off” global_colors_info=”{}”]<\/p>\n Alzheimer’s disease is a progressive brain disorder that leads to a gradual and irreversible decline in memory and cognitive functions. At present, the drugs available to treat it are not very effective, hence the need to develop new products that act on the symptoms.<\/p>\n Scientists are focusing on the development of cognitive\/memory criteria\/markers used in a number of experimental models that artificially induce transient Alzheimer-like disorders.<\/p>\n The use of total sleep deprivation is a good candidate as a physiological model. Various total sleep deprivation studies have been conducted in healthy volunteers for periods ranging from 24 to 72 hours. The 24-hour sleep deprivation model seems to be the best candidate.<\/p>\n The project lasted six years (2010-2015). MEDES was involved in a clinical study at the beginning of the project.<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.19.1″ _module_preset=”default” background_enable_image=”off” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/12\/Capture-decran-2022-12-02-110321.png” alt=”Etude d’immersion s\u00e8che f\u00e9minine – 2021″ title_text=”Etude d’immersion s\u00e8che f\u00e9minine – 2021″ force_fullwidth=”on” disabled_on=”off|off|off” _builder_version=”4.19.1″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” use_background_color_gradient=”on” background_color_gradient_stops=”#256c9e 0%|#1a5d90 100%” custom_padding=”60px||60px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” make_equal=”on” _builder_version=”4.19.1″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.19.1″ _module_preset=”default” background_enable_image=”off” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”margin-bottom: 30px !important”][et_pb_text admin_label=”Au dernier trimestre 2021″ _builder_version=”4.19.3″ text_text_color=”#FFFFFF” header_2_text_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” locked=”off” global_colors_info=”{}”]<\/p>\n The main objectives of the project were to:<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”60px||60px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” locked=”off” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” make_equal=”on” custom_padding_last_edited=”off|tablet” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”on|tablet” custom_css_main_element_tablet=”margin-bottom: 30px !important;” custom_css_main_element_phone=”margin-bottom: 30px !important;”][et_pb_text admin_label=”Pourquoi une immersion s\u00e8che ?” _builder_version=”4.21.0″ header_2_text_align=”right” background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” header_2_text_align_tablet=”left” header_2_text_align_phone=”left” header_2_text_align_last_edited=”on|tablet” text_orientation_tablet=”left” text_orientation_phone=”left” text_orientation_last_edited=”on|tablet” locked=”off” global_colors_info=”{}”]<\/p>\n The study was carried out on 12 male volunteers aged between 25 and 40 years. They were successively hospitalised five times, each for a period of 48 hours.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|tablet” _builder_version=”4.19.1″ _module_preset=”default” background_color=”#FFFFFF” use_background_color_gradient=”on” background_color_gradient_stops=”#f2f2f2 0%|#ffffff 100%” custom_margin=”|0px||0px|false|true” custom_margin_tablet=”|0px||0px|false|true” custom_margin_phone=”|0px||0px|false|true” custom_margin_last_edited=”on|desktop” custom_padding=”11px||11px|0px|true|false” custom_padding_tablet=”40px||40px||false|false” custom_padding_phone=”30px||30px||true|false” locked=”off” global_colors_info=”{}” custom_css_after_last_edited=”off|desktop”][et_pb_row _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_divider color=”rgba(17,88,148,0.24)” _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” custom_padding_last_edited=”off|desktop” _builder_version=”4.17.4″ _module_preset=”default” width=”61%” custom_margin=”||||false|false” custom_margin_tablet=”||40px||false|false” custom_margin_phone=”||30px||false|false” custom_margin_last_edited=”off|desktop” custom_padding=”0px||0px||true|false” custom_padding_tablet=”30px||||false|false” custom_padding_phone=”20px||||false|false” custom_css_main_element=”-webkit-box-align: center;|| -ms-flex-align: center;|| align-items: center;” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”on|tablet” custom_css_main_element_tablet=”margin-bottom: 20px;” custom_css_main_element_phone=”margin-bottom: 20px;”][et_pb_text admin_label=”Pour aller plus loin” _builder_version=”4.21.0″ _module_preset=”default” text_font=”Open Sans|700|||||||” text_font_size=”24px” header_text_color=”#115994″ header_font_size=”52px” header_2_font=”||||||||” header_2_text_align=”left” header_2_text_color=”#000000″ header_2_font_size=”22px” custom_margin=”||10px||false|false” custom_margin_tablet=”||0px||false|false” custom_margin_phone=”||0px||false|false” custom_margin_last_edited=”on|tablet” animation_direction=”bottom” header_font_size_tablet=”40px” header_font_size_phone=”30px” header_2_text_align_tablet=”center” header_2_text_align_phone=”center” header_2_text_align_last_edited=”on|tablet” header_2_font_size_tablet=”18px” header_2_font_size_phone=”20px” animation_duration_tablet=”0ms” animation_duration_phone=”0ms” animation_duration_last_edited=”on|tablet” animation_intensity_slide_tablet=”” animation_intensity_slide_phone=”0%” animation_intensity_slide_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.17.4″ _module_preset=”default” width=”61%” min_height=”72.7px” custom_padding=”||1px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.21.0″ _module_preset=”default” text_font=”Open Sans||||||||” text_text_color=”#000000″ link_option_url=”https:\/\/www.imi.europa.eu\/projects-results\/project-factsheets\/pharma-cog” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_divider color=”rgba(17,88,148,0.24)” _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_class=”sectionFixe” _builder_version=”4.18.0″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” positioning=”none” position_origin_f=”center_right” horizontal_offset=”0px” custom_padding=”0px||0px||true|false” custom_css_main_element=”position: fixed !important;||right: 0 !important;||left: unset !important;||top: 57%!important;||transform: translateY(-50%);” locked=”off” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” _builder_version=”4.18.0″ _module_preset=”default” width=”100%” max_width=”100%” custom_padding=”0px||0px||true|false” custom_css_main_element=” overflow: visible !important;” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb image=”https:\/\/www.medes.fr\/wp-content\/uploads\/2023\/04\/Sans-titre-18.png” icon_placement=”left” image_icon_width=”50px” module_class=”boutonFixe” _builder_version=”4.20.2″ _module_preset=”default” background_color=”#ffae00″ image_icon_custom_margin=”||||false|false” image_icon_custom_padding=”|14px|||false|false” custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/en\/ressources\/news\/” global_colors_info=”{}”]<\/p>\n Nos actualit\u00e9s<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”||divi||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.20.2″ _module_preset=”default” background_color=”#D6D6D6″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/en\/our-projects\/” global_colors_info=”{}”]<\/p>\n Nos projets<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”u||divi||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.20.2″ _module_preset=”default” background_color=”#5e5e5e” custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/en\/contact\/” global_colors_info=”{}”]<\/p>\n Une question ?<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”||fa||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.20.2″ _module_preset=”default” background_color=”gcid-54b54a1e-9ad0-4545-b0eb-2cf1c6cd3982″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/en\/space-clinic\/become-a-volunteer\/” global_colors_info=”{%22gcid-54b54a1e-9ad0-4545-b0eb-2cf1c6cd3982%22:%91%22background_color%22%93}”]<\/p>\n Devenir volontaire ?<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”||fa||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.19.5″ _module_preset=”default” background_color=”gcid-4eb119fd-82df-4fd0-ae59-ab7f1c508199″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/en\/space-clinic\/clinical-studies\/” global_colors_info=”{%22gcid-4eb119fd-82df-4fd0-ae59-ab7f1c508199%22:%91%22background_color%22%93}”]<\/p>\n Nos \u00e9tudes cliniques<\/p>\n [\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”s||divi||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”28px” module_class=”boutonFixe” _builder_version=”4.20.2″ _module_preset=”default” background_color=”#002130″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/a-la-une\/recrutement\/” global_colors_info=”{}”]<\/p>\n Urgent ! Recrutement volontaires<\/p>\n [\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Clinical study on sleep deprivation<\/p>\n","protected":false},"author":1,"featured_media":12727,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[86,79,54,75],"project_tag":[],"class_list":["post-13275","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-clinical-research","project_category-clinical-study","project_category-la-recherche-clinique","project_category-space-clinic"],"acf":[],"yoast_head":"\nContext<\/h2>\n
Objectives<\/h2>\n
\n
<\/ul>\n
Study configuration<\/h2>\n
\n
<\/ul>\n
More information<\/h3>\n
\n