{"id":13272,"date":"2012-12-02T10:47:26","date_gmt":"2012-12-02T09:47:26","guid":{"rendered":"https:\/\/www.medes.fr\/project\/cpmm-study-2012\/"},"modified":"2023-06-05T11:44:37","modified_gmt":"2023-06-05T09:44:37","slug":"cpmm-study-2012","status":"publish","type":"project","link":"https:\/\/www.medes.fr\/en\/project\/cpmm-study-2012\/","title":{"rendered":"CPMM study (2012)"},"content":{"rendered":"

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Evaluation of an ultrasonic tonometer measuring carotid and femoral artery parameters<\/span><\/p>\n

[\/et_pb_text][et_pb_divider color=”#ffae00″ divider_weight=”5px” _builder_version=”4.18.0″ _module_preset=”default” width=”300px” width_tablet=”250px” width_phone=”150px” width_last_edited=”on|phone” module_alignment=”center” custom_margin=”||0px||false|false” custom_padding=”||2px||false|false” module_alignment_tablet=”center” module_alignment_phone=”left” module_alignment_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text module_class=”projectCategorie” _builder_version=”4.18.0″ _dynamic_attributes=”content” _module_preset=”default” text_font_size=”14px” link_text_color=”#444444″ text_orientation=”center” text_orientation_tablet=”center” text_orientation_phone=”left” text_orientation_last_edited=”on|phone” global_colors_info=”{}” link_text_color__hover_enabled=”on|hover” link_text_color__hover=”#115894″]@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9jYXRlZ29yaWVzIiwic2V0dGluZ3MiOnsiYmVmb3JlIjoiIiwiYWZ0ZXIiOiIiLCJsaW5rX3RvX3Rlcm1fcGFnZSI6Im9uIiwic2VwYXJhdG9yIjoiICIsImNhdGVnb3J5X3R5cGUiOiJwcm9qZWN0X2NhdGVnb3J5In19@[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” module_class=”rowDetails” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”off|phone”][et_pb_blurb title=”Date : ” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.19.5″ _module_preset=”default” header_text_color=”#444444″ animation=”off” global_colors_info=”{}”]<\/p>\n

2012<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”State of progress :” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Ended<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Objective : ” use_icon=”on” font_icon=”||fa||900″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Evaluation of an ultrasonic tonometer measuring carotid\u00a0<\/span><\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Partners : ” use_icon=”on” font_icon=”||fa||400″ icon_color=”#115894″ icon_placement=”left” image_icon_width=”30px” image_icon_width_tablet=”28px” image_icon_width_phone=”25px” image_icon_width_last_edited=”on|phone” _builder_version=”4.21.0″ _module_preset=”default” header_text_color=”#444444″ animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

ESA, MEDES, Verhaert<\/p>\n

[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”60px||60px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” global_colors_info=”{}”][et_pb_row _builder_version=”4.18.0″ _module_preset=”default” custom_margin=”||10px||false|false” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”MEDES a men\u00e9 pour l’ESA” _builder_version=”4.19.3″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” locked=”off” global_colors_info=”{}”]<\/p>\n

Context<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”2_3,1_3″ use_custom_gutter=”on” make_equal=”on” _builder_version=”4.19.1″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”2_3″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”on|tablet” custom_css_main_element_tablet=”margin-bottom: 30px !important” custom_css_main_element_phone=”margin-bottom: 30px !important”][et_pb_text admin_label=”Au dernier trimestre 2021″ _builder_version=”4.19.1″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” locked=”off” global_colors_info=”{}”]<\/p>\n

When astronauts return to Earth after space flights of various durations, they frequently encounter symptoms such as dizziness when they change position; for example when moving from a sitting to a standing position, going from lying down to standing, or even when they remain in a standing position for long periods.\u00a0<\/span>This is known as orthostatic intolerance.\u00a0<\/span><\/strong>It can be explained by a loss of the cardiovascular system\u2019s ability to maintain a sufficient supply of oxygen to the brain. Symptoms can range from dizziness through to loss of consciousness.<\/p>\n

 <\/p>\n

Study objectives<\/h2>\n

 <\/p>\n

In order to better assess these phenomena at arterial level under very specific conditions (microgravity, clinical simulation studies, parabolic flights, etc.),\u00a0<\/span>the European Space Agency decided to develop different devices aiming to better understand and analyse the physiological mechanisms involved in these symptoms.<\/strong>\u00a0<\/span>In this regard, and working closely with scientists from the University of Ghent, the Belgian company Verhaert is developing a device that combines the principles of tonometry and Doppler ultrasound to measure different parameters that characterise the physiological condition of the arteries. In particular, this device should measure blood pressure at various sites, arterial diameter, ejection time and pulse wave velocity, all in a completely non-invasive manner.<\/p>\n

 <\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.19.1″ _module_preset=”default” background_enable_image=”off” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/12\/RIMG0042_MD.jpg” title_text=”Etude CPMM – LBNP” _builder_version=”4.19.1″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” use_background_color_gradient=”on” background_color_gradient_stops=”#256c9e 0%|#1a5d90 100%” custom_padding=”60px||60px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” make_equal=”on” _builder_version=”4.19.1″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.19.1″ _module_preset=”default” background_enable_image=”off” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”margin-bottom: 30px !important”][et_pb_text admin_label=”Au dernier trimestre 2021″ _builder_version=”4.19.1″ text_text_color=”#FFFFFF” header_2_text_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_padding=”|||18px|false|false” border_width_left=”7px” border_color_left=”#1FE0BA” locked=”off” global_colors_info=”{}”]<\/p>\n

Apparatus tested<\/strong> : CPMM or tonometer and an ultrasound probe. This device records fine variations in pressure in relation to the sensor. It records movements linked to the heartbeat and the movement of blood in the vessels.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”60px||60px||true|false” custom_padding_tablet=”40px||40px||true|false” custom_padding_phone=”30px||30px||true|false” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” make_equal=”on” custom_padding_last_edited=”off|tablet” _builder_version=”4.18.0″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”on|tablet” custom_css_main_element_tablet=”margin-bottom: 30px !important;” custom_css_main_element_phone=”margin-bottom: 30px !important;”][et_pb_text admin_label=”Pourquoi une immersion s\u00e8che ?” _builder_version=”4.21.0″ header_2_text_align=”right” background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”right” header_2_text_align_tablet=”left” header_2_text_align_phone=”left” header_2_text_align_last_edited=”on|tablet” text_orientation_tablet=”left” text_orientation_phone=”left” text_orientation_last_edited=”on|tablet” locked=”off” global_colors_info=”{}”]<\/p>\n

Implementation of the study<\/h2>\n

\n

Fourteen male and female subjects aged from 20 to 40 years took part in this study.<\/p>\n

The subject lay on a kind of bed that can be mechanically lifted (a device called a tilt table). This tilt table is equipped with a \u201cLow Body Negative Pressure\u201d (LBNP) system, a large box in which the subject places his\/her legs and pelvis. This system can then apply negative pressure (like a vacuum) to the lower part of the body. A neoprene skirt, similar to the one fitted to kayaks, ensures that the box is air-tight. A variety of equipment is then attached to the subject: ultrasound probes, tonometry sensors, Finapres monitor, Dynamap monitor, tilt table<\/p>\n

Measurements from the LBNP during the tilt test are then recorded.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}” custom_css_main_element_last_edited=”on|tablet” custom_css_main_element_tablet=”margin-bottom: 30px !important;” custom_css_main_element_phone=”margin-bottom: 30px !important;”][et_pb_image src=”https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/12\/DSC00534_MD.jpg” title_text=”Etude CPMM LBNP” align=”right” _builder_version=”4.19.1″ _module_preset=”default” width=”84%” max_height=”1000px” animation_style=”fade” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_class=”sectionFixe” _builder_version=”4.18.0″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” positioning=”none” position_origin_f=”center_right” horizontal_offset=”0px” custom_padding=”0px||0px||true|false” custom_css_main_element=”position: fixed !important;||right: 0 !important;||left: unset !important;||top: 57%!important;||transform: translateY(-50%);” locked=”off” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” _builder_version=”4.18.0″ _module_preset=”default” width=”100%” max_width=”100%” custom_padding=”0px||0px||true|false” custom_css_main_element=” overflow: visible !important;” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb image=”https:\/\/www.medes.fr\/wp-content\/uploads\/2023\/04\/Sans-titre-18.png” icon_placement=”left” image_icon_width=”50px” module_class=”boutonFixe” _builder_version=”4.20.2″ _module_preset=”default” background_color=”#ffae00″ image_icon_custom_margin=”||||false|false” image_icon_custom_padding=”|14px|||false|false” custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/en\/ressources\/news\/” global_colors_info=”{}”]<\/p>\n

Nos actualit\u00e9s<\/p>\n

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Nos projets<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”u||divi||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.20.2″ _module_preset=”default” background_color=”#5e5e5e” custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/en\/contact\/” global_colors_info=”{}”]<\/p>\n

Une question ?<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”||fa||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.20.2″ _module_preset=”default” background_color=”gcid-54b54a1e-9ad0-4545-b0eb-2cf1c6cd3982″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/en\/space-clinic\/become-a-volunteer\/” global_colors_info=”{%22gcid-54b54a1e-9ad0-4545-b0eb-2cf1c6cd3982%22:%91%22background_color%22%93}”]<\/p>\n

Devenir volontaire ?<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”||fa||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”30px” module_class=”boutonFixe” _builder_version=”4.19.5″ _module_preset=”default” background_color=”gcid-4eb119fd-82df-4fd0-ae59-ab7f1c508199″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/en\/space-clinic\/clinical-studies\/” global_colors_info=”{%22gcid-4eb119fd-82df-4fd0-ae59-ab7f1c508199%22:%91%22background_color%22%93}”]<\/p>\n

Nos \u00e9tudes cliniques<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”s||divi||400″ icon_color=”#FFFFFF” icon_placement=”left” image_icon_width=”28px” module_class=”boutonFixe” _builder_version=”4.20.2″ _module_preset=”default” background_color=”#002130″ custom_padding=”10px|10px|10px|10px|true|true” animation=”off” link_option_url=”https:\/\/www.medes.fr\/a-la-une\/recrutement\/” global_colors_info=”{}”]<\/p>\n

Urgent ! Recrutement volontaires<\/p>\n

[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

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