{"id":13229,"date":"2021-11-30T15:43:11","date_gmt":"2021-11-30T14:43:11","guid":{"rendered":"https:\/\/www.medes.fr\/project\/mnx-bed-rest-study-2012-2013\/"},"modified":"2023-06-05T10:52:33","modified_gmt":"2023-06-05T08:52:33","slug":"mnx-bed-rest-study-2012-2013","status":"publish","type":"project","link":"https:\/\/www.medes.fr\/en\/project\/mnx-bed-rest-study-2012-2013\/","title":{"rendered":"MNX bed rest study (2012-2013)"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/06\/AdobeStock_279577524-compressed-scaled.jpg&#8221; custom_padding=&#8221;40px||40px||true|false&#8221; custom_padding_tablet=&#8221;30px||30px||true|false&#8221; custom_padding_phone=&#8221;30px||30px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; 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icon_color=&#8221;#115894&#8243; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;30px&#8221; image_icon_width_tablet=&#8221;28px&#8221; image_icon_width_phone=&#8221;25px&#8221; image_icon_width_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#444444&#8243; animation=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>2021<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb title=&#8221;State of progress :&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf14a;||fa||400&#8243; icon_color=&#8221;#115894&#8243; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;30px&#8221; image_icon_width_tablet=&#8221;28px&#8221; image_icon_width_phone=&#8221;25px&#8221; image_icon_width_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#444444&#8243; animation=&#8221;off&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Ended<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb title=&#8221;Objective : &#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf140;||fa||900&#8243; icon_color=&#8221;#115894&#8243; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;30px&#8221; image_icon_width_tablet=&#8221;28px&#8221; image_icon_width_phone=&#8221;25px&#8221; image_icon_width_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#444444&#8243; animation=&#8221;off&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Study of the effects of space flight on the human body<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb title=&#8221;Partner :&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf2b5;||fa||400&#8243; icon_color=&#8221;#115894&#8243; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;30px&#8221; image_icon_width_tablet=&#8221;28px&#8221; image_icon_width_phone=&#8221;25px&#8221; image_icon_width_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#444444&#8243; animation=&#8221;off&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>ESA<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;60px||60px||true|false&#8221; custom_padding_tablet=&#8221;40px||40px||true|false&#8221; custom_padding_phone=&#8221;30px||30px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||10px||false|false&#8221; custom_padding=&#8221;0px||0px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;MEDES a men\u00e9 pour l&#8217;ESA&#8221; _builder_version=&#8221;4.19.1&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>The \u201cMedium duration Nutrition and vibration eXercise\u201d (<span class=\"highlight\">MNX<\/span>) study was part of a research programme being conducted under the leadership of the French and European space agencies.<\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_3,1_3&#8243; use_custom_gutter=&#8221;on&#8221; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||0px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; custom_css_main_element_last_edited=&#8221;on|tablet&#8221; custom_css_main_element_tablet=&#8221;margin-bottom: 30px !important&#8221; custom_css_main_element_phone=&#8221;margin-bottom: 30px !important&#8221;][et_pb_text admin_label=&#8221;Au dernier trimestre 2021&#8243; _builder_version=&#8221;4.20.2&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Its main aim was to study the effectiveness of two methods for mitigating the effects of microgravity to which astronauts are subjected (countermeasures):<\/p>\n<ul class=\"disc\">\n<li>exercising the lower limbs (&#8220;squats&#8221;) under resistance, on a vibrating platform. This exercise was conducted twice a week,<\/li>\n<li>the same physical exercise programme combined with protein and potassium bicarbonate supplementation in the daily diet.<\/li>\n<\/ul>\n<p>Twelve volunteers were recruited for this study. They underwent three periods of hospitalisation each lasting 35 days (including 21 days of bed rest each time). Each period was separated from the next by a period of 4 months, making the total study duration 1 year.<\/p>\n<p>Nine teams of scientists took part in the study.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; background_enable_image=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/11\/Capture-decran-2022-11-30-154726.png&#8221; title_text=&#8221;Capture d\u2019\u00e9cran 2022-11-30 154726&#8243; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_stops=&#8221;#256c9e 0%|#1a5d90 100%&#8221; custom_padding=&#8221;60px||60px||true|false&#8221; custom_padding_tablet=&#8221;40px||40px||true|false&#8221; custom_padding_phone=&#8221;30px||30px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; use_custom_gutter=&#8221;on&#8221; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-28px||||false|false&#8221; custom_margin_tablet=&#8221;-28px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; background_enable_image=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; custom_css_main_element_last_edited=&#8221;on|phone&#8221; custom_css_main_element_phone=&#8221;margin-bottom: 30px !important&#8221;][et_pb_image src=&#8221;https:\/\/www.medes.fr\/wp-content\/uploads\/2023\/06\/Key-figures-MNX.png&#8221; title_text=&#8221;Key figures MNX&#8221; align=&#8221;right&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;0px||0px||true|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; background_enable_image=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; custom_css_main_element_last_edited=&#8221;on|phone&#8221; custom_css_main_element_phone=&#8221;margin-bottom: 30px !important&#8221;][et_pb_text _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;10px||-1px||false|false&#8221; custom_margin_tablet=&#8221;10px||-1px||false|false&#8221; custom_margin_phone=&#8221;0px||0px||true|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;62px||||false|false&#8221; custom_padding_tablet=&#8221;62px||||false|false&#8221; custom_padding_phone=&#8221;0px||0px||true|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h2><span style=\"color: #ffffff;\">Key figures for the study<\/span><\/h2>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;60px||60px||true|false&#8221; custom_padding_tablet=&#8221;40px||40px||true|false&#8221; custom_padding_phone=&#8221;30px||30px||true|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_3,1_3&#8243; use_custom_gutter=&#8221;on&#8221; make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;off|tablet&#8221; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||0px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; custom_css_main_element_last_edited=&#8221;on|tablet&#8221; custom_css_main_element_tablet=&#8221;margin-bottom: 30px !important;&#8221; custom_css_main_element_phone=&#8221;margin-bottom: 30px !important;&#8221;][et_pb_text admin_label=&#8221;Pourquoi une immersion s\u00e8che ?&#8221; _builder_version=&#8221;4.21.0&#8243; header_2_text_align=&#8221;right&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; text_orientation=&#8221;right&#8221; hover_enabled=&#8221;0&#8243; header_2_text_align_tablet=&#8221;left&#8221; header_2_text_align_phone=&#8221;left&#8221; header_2_text_align_last_edited=&#8221;on|tablet&#8221; text_orientation_tablet=&#8221;left&#8221; text_orientation_phone=&#8221;left&#8221; text_orientation_last_edited=&#8221;on|tablet&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h2 style=\"text-align: left;\">Implementation of the study<\/h2>\n<p style=\"text-align: left;\">The 12 study volunteers were divided into three groups as follows:<\/p>\n<ul class=\"disc\" style=\"text-align: left;\">\n<li><strong>Exercise and vibration group:<\/strong><span>\u00a0<\/span>during the bed-rest period, the volunteers from this group underwent physical training twice a week (&#8220;squat&#8221; type exercises, i.e. pushing with their legs) lying down on a vibrating platform on a machine specially designed for this purpose.<\/li>\n<li><strong>Exercise and vibration plus nutrition group:<\/strong><span>\u00a0<\/span>during the bed-rest period, the volunteers in this group underwent the same physical training as the previous group, but received a slightly different daily diet: the amount of protein was increased with additional intake in the form of whey protein and potassium bicarbonate. This supplementation was administered with main meals and snacks (6 times\/day).<\/li>\n<li><strong>Control group:<\/strong><span>\u00a0<\/span>this group served as a control for the experiment. The subjects in this group did not do exercise sessions on the vibrating platform and followed a standard controlled diet. By comparison, this group served to assess the effect of the two types of countermeasures on each volunteer.<\/li>\n<\/ul>\n<p style=\"text-align: left;\">This was a cross-over study, meaning that each of the 12 volunteers acted as their own control, and changed group each period. Lots were drawn to determine the order in which they changed between the three groups.<\/p>\n<p style=\"text-align: left;\">\n<p style=\"text-align: left;\">Each hospitalisation period of 35 days was broken down into three phases:<\/p>\n<ul class=\"disc\" style=\"text-align: left;\">\n<li>An ambulatory control period of 7 days before bed rest,<\/li>\n<li>Anti-orthostatic bed rest (inclined at -6\u00b0) for a period of 21 days,<\/li>\n<li>An ambulatory recovery period of 7 days after bed rest.<\/li>\n<\/ul>\n<p style=\"text-align: left;\">\n<p style=\"text-align: left;\">Following each hospitalisation period, the volunteers returned for follow-up visits, 14 days and 28 days after the end of each bed-rest campaig<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; background_enable_image=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/06\/Plateforme-Vibrante.jpg&#8221; alt=&#8221;Vibrating Platform&#8221; title_text=&#8221;Vibrating Platform&#8221; force_fullwidth=&#8221;on&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;60px||||false|false&#8221; custom_margin_tablet=&#8221;60px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_stops=&#8221;#256c9e 0%|#1a5d90 100%&#8221; custom_padding=&#8221;60px||60px||true|false&#8221; custom_padding_tablet=&#8221;40px||40px||true|false&#8221; custom_padding_phone=&#8221;30px||30px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; use_custom_gutter=&#8221;on&#8221; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-28px||||false|false&#8221; custom_margin_tablet=&#8221;-28px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; background_enable_image=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; custom_css_main_element_last_edited=&#8221;on|phone&#8221; custom_css_main_element_phone=&#8221;margin-bottom: 30px !important&#8221;][et_pb_text _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h2 style=\"padding-bottom: 25px; text-align: left;\"><span style=\"color: #ffffff;\">Les protocoles scientifiques<\/span><\/h2>\n<p><span style=\"color: #ffffff;\">Nine research teams studied the mechanisms of the body\u2019s adaptation to 21 days of simulated microgravity and the effect of the two countermeasure protocols on the following physiological systems :<\/span><\/p>\n<p><span style=\"color: #ffffff;\">\u00a0<\/span><\/p>\n<ul class=\"disc\">\n<li><span style=\"color: #ffffff;\"><strong>Metabolic systems<\/strong><strong><\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"color: #ffffff;\"><strong><\/strong><\/span><\/p>\n<ul class=\"disc\">\n<li><span style=\"color: #ffffff;\"><strong>The cardiovascular system and its control mechanisms<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"color: #ffffff;\"><strong><\/strong><\/span><\/p>\n<ul class=\"disc\">\n<li><span style=\"color: #ffffff;\"><strong>The osteoarticular system and muscles<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"color: #ffffff;\"><strong><\/strong><\/span><\/p>\n<ul class=\"disc\">\n<li><span style=\"color: #ffffff;\"><strong>The bloodstream, primarily the mechanisms of blood coagulation<\/strong><\/span><\/li>\n<\/ul>\n<ul class=\"square\"><\/ul>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; background_enable_image=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; custom_css_main_element_last_edited=&#8221;on|phone&#8221; custom_css_main_element_phone=&#8221;margin-bottom: 30px !important&#8221;][et_pb_text _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;99px||||false|false&#8221; custom_margin_tablet=&#8221;99px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||||false|false&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><span style=\"color: #ffffff;\">The main lead scientists who participated in this study are as follows:<\/span><\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/11\/1-1.png&#8221; title_text=&#8221;1&#8243; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;60px||60px||true|false&#8221; custom_padding_tablet=&#8221;40px||40px||true|false&#8221; custom_padding_phone=&#8221;30px||30px||true|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;3_5,2_5&#8243; use_custom_gutter=&#8221;on&#8221; make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; width=&#8221;95.3%&#8221; width_tablet=&#8221;95.3%&#8221; width_phone=&#8221;80%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;|auto|27px|auto||&#8221; custom_margin_tablet=&#8221;|auto|27px|auto||&#8221; custom_margin_phone=&#8221;0px||0px||true|true&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px|34px|true|false&#8221; custom_padding_tablet=&#8221;0px||0px|34px|true|false&#8221; custom_padding_phone=&#8221;|0px||0px|true|true&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; custom_css_main_element_last_edited=&#8221;on|tablet&#8221; custom_css_main_element_tablet=&#8221;margin-bottom: 30px !important;&#8221; custom_css_main_element_phone=&#8221;margin-bottom: 30px !important;&#8221;][et_pb_text admin_label=&#8221;Pourquoi une immersion s\u00e8che ?&#8221; _builder_version=&#8221;4.21.0&#8243; header_2_text_align=&#8221;right&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; text_orientation=&#8221;right&#8221; width=&#8221;94.6%&#8221; custom_margin=&#8221;|-112px||-30px|false|false&#8221; custom_margin_tablet=&#8221;|-107px||-44px|false|false&#8221; custom_margin_phone=&#8221;|0px||0px|false|true&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||||false|false&#8221; hover_enabled=&#8221;0&#8243; header_2_text_align_tablet=&#8221;left&#8221; header_2_text_align_phone=&#8221;left&#8221; header_2_text_align_last_edited=&#8221;on|tablet&#8221; text_orientation_tablet=&#8221;left&#8221; text_orientation_phone=&#8221;left&#8221; text_orientation_last_edited=&#8221;on|tablet&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h2>Nutrition during the study<\/h2>\n<p style=\"text-align: left;\"><span>Food and everything that relates to it (health, social interaction, etc.) is essential for astronauts on long-duration missions.<\/span><\/p>\n<p><em>During a long-duration mission, eating right is vital for theastronauts. It\u2019s fuel for their bodies, but meal times together are also good for morale. In microgravity, the energy balance is negative. Astronauts lose weight, either because they don\u2019t eat enough or because they do a lot of exercise. In the long term, their performance could be affected and mission success compromised. When preparing a journey to Mars, food is both a health and logistics issue. Taking the wrong amount would be critical for the crew\u2019s health and the cost of the mission&#8221;, explains Marie-Pierre Bareille, head of the bedrest programme at MEDES<span>\u00a0<\/span>(Source: excerpt from the article<span>\u00a0<\/span>\u201cWhat\u2019s on the menu?\u201d, Cnes Mag n\u00b058).<\/em><\/p>\n<p>The European Space Agency (ESA) has therefore defined a long-term strategy to standardise the conditions of bed-rest studies especially with regard to nutrition (Working Group on Space Nutrition of the European Space Agency: Ms M. Heer, Mr S. Blanc and Dr. G. Biolo).<\/p>\n<p>During these experiments, nutritional intakes are now fully monitored and controlled.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; background_enable_image=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.medes.fr\/wp-content\/uploads\/2022\/11\/Capture-decran-2022-11-30-162457.png&#8221; alt=&#8221;Vibrating Platform&#8221; title_text=&#8221;Capture d\u2019\u00e9cran 2022-11-30 162457&#8243; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; width=&#8221;146%&#8221; width_tablet=&#8221;146%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|phone&#8221; max_width=&#8221;181%&#8221; max_width_tablet=&#8221;181%&#8221; max_width_phone=&#8221;100%&#8221; max_width_last_edited=&#8221;on|phone&#8221; height=&#8221;407px&#8221; height_tablet=&#8221;407px&#8221; height_phone=&#8221;100%&#8221; height_last_edited=&#8221;on|phone&#8221; max_height=&#8221;1000px&#8221; max_height_tablet=&#8221;1000px&#8221; max_height_phone=&#8221;100%&#8221; max_height_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;91px|38px||-125px|false|false&#8221; custom_margin_tablet=&#8221;91px|38px||-125px|false|false&#8221; custom_margin_phone=&#8221;0px|auto||auto|false|true&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;|||0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; module_class=&#8221;sectionFixe&#8221; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; positioning=&#8221;none&#8221; position_origin_f=&#8221;center_right&#8221; horizontal_offset=&#8221;0px&#8221; custom_padding=&#8221;0px||0px||true|false&#8221; custom_css_main_element=&#8221;position: fixed !important;||right: 0 !important;||left: unset !important;||top: 57%!important;||transform: translateY(-50%);&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;1&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; max_width=&#8221;100%&#8221; custom_padding=&#8221;0px||0px||true|false&#8221; custom_css_main_element=&#8221;    overflow: visible !important;&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb image=&#8221;https:\/\/www.medes.fr\/wp-content\/uploads\/2023\/04\/Sans-titre-18.png&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;50px&#8221; module_class=&#8221;boutonFixe&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#ffae00&#8243; image_icon_custom_margin=&#8221;||||false|false&#8221; image_icon_custom_padding=&#8221;|14px|||false|false&#8221; custom_padding=&#8221;10px|10px|10px|10px|true|true&#8221; animation=&#8221;off&#8221; link_option_url=&#8221;https:\/\/www.medes.fr\/en\/ressources\/news\/&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Nos actualit\u00e9s<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xe101;||divi||400&#8243; icon_color=&#8221;#FFFFFF&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;30px&#8221; module_class=&#8221;boutonFixe&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#D6D6D6&#8243; custom_padding=&#8221;10px|10px|10px|10px|true|true&#8221; animation=&#8221;off&#8221; link_option_url=&#8221;https:\/\/www.medes.fr\/en\/our-projects\/&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Nos projets<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#x75;||divi||400&#8243; icon_color=&#8221;#FFFFFF&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;30px&#8221; module_class=&#8221;boutonFixe&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#5e5e5e&#8221; custom_padding=&#8221;10px|10px|10px|10px|true|true&#8221; animation=&#8221;off&#8221; link_option_url=&#8221;https:\/\/www.medes.fr\/en\/contact\/&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Une question ?<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf007;||fa||400&#8243; icon_color=&#8221;#FFFFFF&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;30px&#8221; module_class=&#8221;boutonFixe&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;gcid-54b54a1e-9ad0-4545-b0eb-2cf1c6cd3982&#8243; custom_padding=&#8221;10px|10px|10px|10px|true|true&#8221; animation=&#8221;off&#8221; link_option_url=&#8221;https:\/\/www.medes.fr\/en\/space-clinic\/become-a-volunteer\/&#8221; global_colors_info=&#8221;{%22gcid-54b54a1e-9ad0-4545-b0eb-2cf1c6cd3982%22:%91%22background_color%22%93}&#8221;]<\/p>\n<p>Devenir volontaire ?<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf15c;||fa||400&#8243; icon_color=&#8221;#FFFFFF&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;30px&#8221; module_class=&#8221;boutonFixe&#8221; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;gcid-4eb119fd-82df-4fd0-ae59-ab7f1c508199&#8243; custom_padding=&#8221;10px|10px|10px|10px|true|true&#8221; animation=&#8221;off&#8221; link_option_url=&#8221;https:\/\/www.medes.fr\/en\/space-clinic\/clinical-studies\/&#8221; global_colors_info=&#8221;{%22gcid-4eb119fd-82df-4fd0-ae59-ab7f1c508199%22:%91%22background_color%22%93}&#8221;]<\/p>\n<p>Nos \u00e9tudes cliniques<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb use_icon=&#8221;on&#8221; font_icon=&#8221;&#x73;||divi||400&#8243; icon_color=&#8221;#FFFFFF&#8221; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;28px&#8221; module_class=&#8221;boutonFixe&#8221; _builder_version=&#8221;4.20.2&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#002130&#8243; custom_padding=&#8221;10px|10px|10px|10px|true|true&#8221; animation=&#8221;off&#8221; link_option_url=&#8221;https:\/\/www.medes.fr\/a-la-une\/recrutement\/&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Urgent ! Recrutement volontaires<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The \u201cMedium duration Nutrition and vibration eXercise\u201d (MNX) study was part of a research programme being conducted under the leadership of the French and European space agencies.<\/p>\n","protected":false},"author":1,"featured_media":12501,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[80,86,79,43,76,75],"project_tag":[],"class_list":["post-13229","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-bed-rest-study","project_category-clinical-research","project_category-clinical-study","project_category-contre-mesures","project_category-countermeasures","project_category-space-clinic"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - 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